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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PRC1 All Species: 29.67
Human Site: S4 Identified Species: 65.27
UniProt: O43663 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43663 NP_003972.1 620 71607 S4 _ _ _ _ M R R S E V L A E E S
Chimpanzee Pan troglodytes XP_510600 770 87232 S168 G A S A M R R S E V L A E E S
Rhesus Macaque Macaca mulatta XP_001098763 640 74381 S4 _ _ _ _ M R R S E V L A E E S
Dog Lupus familis XP_849989 620 71878 S4 _ _ _ _ M R R S E V L A E E S
Cat Felis silvestris
Mouse Mus musculus Q99K43 603 70244 S4 _ _ _ _ M R R S E V L A D E S
Rat Rattus norvegicus NP_001100999 606 70580 S4 _ _ _ _ M R R S E V L A D E S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001073221 262 30135
Frog Xenopus laevis NP_001080868 609 71186 S4 _ _ _ _ M R K S E A I A A E S
Zebra Danio Brachydanio rerio NP_956528 605 70353 S4 _ _ _ _ M R K S E V I A A E S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572659 607 71048 A8 M L S S E H K A R I L A L T A
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_785901 748 86941 R6 _ _ M E A K R R E S M K M E I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 78.3 89.8 93 N.A. 81.2 81.2 N.A. N.A. 28.5 61.9 59 N.A. 22.2 N.A. N.A. 31.2
Protein Similarity: 100 78.4 92.5 95.8 N.A. 88.3 88.8 N.A. N.A. 35.6 76.2 73.3 N.A. 43.5 N.A. N.A. 48.1
P-Site Identity: 100 73.3 100 100 N.A. 90.9 90.9 N.A. N.A. 0 63.6 72.7 N.A. 13.3 N.A. N.A. 23
P-Site Similarity: 100 80 100 100 N.A. 100 100 N.A. N.A. 0 81.8 90.9 N.A. 40 N.A. N.A. 38.4
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 10 10 0 0 10 0 10 0 82 19 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 19 0 0 % D
% Glu: 0 0 0 10 10 0 0 0 82 0 0 0 37 82 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 10 19 0 0 0 10 % I
% Lys: 0 0 0 0 0 10 28 0 0 0 0 10 0 0 0 % K
% Leu: 0 10 0 0 0 0 0 0 0 0 64 0 10 0 0 % L
% Met: 10 0 10 0 73 0 0 0 0 0 10 0 10 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 73 64 10 10 0 0 0 0 0 0 % R
% Ser: 0 0 19 10 0 0 0 73 0 10 0 0 0 0 73 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % T
% Val: 0 0 0 0 0 0 0 0 0 64 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 73 73 64 64 0 0 0 0 0 0 0 0 0 0 0 % _